Emerging Importance of Neuron-Satellite Glia Interactions within Trigeminal Ganglia in Craniofacial Pain
نویسندگان
چکیده
منابع مشابه
Emerging Importance of Neuron-Satellite Glia Interactions within Trigeminal Ganglia in Craniofacial Pain
Pain in the head and face, which can be very severe and debilitating, often involves activation of trigeminal ganglion nerves. The craniofacial symptoms can manifest as acute or transient conditions such as toothaches and headaches, or can transform into more chronic conditions such as migraine, rhinosinusitis, temporomandibular joint (TMJ) disorder, or trigeminal neuralgia. Traditionally, it i...
متن کاملNeuron-interacting satellite glial cells in human trigeminal ganglia have an APC phenotype.
Satellite glial cells (SGC) in sensory ganglia tightly envelop the neuronal cell body to form discrete anatomical units. This type of glial cell is considered neuroectoderm-derived and provides physical support to neuron somata. There are scattered hints in the literature suggesting that SGC have an immune-related function within sensory ganglia. In this study, we addressed the hypothesis that ...
متن کاملNeuron-glia signaling in trigeminal ganglion: implications for migraine pathology.
OBJECTIVE The goal of this study was to investigate neuronal-glial cell signaling in trigeminal ganglia under basal and inflammatory conditions using an in vivo model of trigeminal nerve activation. BACKGROUND Activation of trigeminal ganglion nerves and release of calcitonin gene-related peptide (CGRP) are implicated in the pathology of migraine. Cell bodies of trigeminal neurons reside in t...
متن کاملGlia–neuron interactions in the mammalian retina
The mammalian retina provides an excellent opportunity to study glia-neuron interactions and the interactions of glia with blood vessels. Three main types of glial cells are found in the mammalian retina that serve to maintain retinal homeostasis: astrocytes, Müller cells and resident microglia. Müller cells, astrocytes and microglia not only provide structural support but they are also involve...
متن کاملPurinergic Signalling in Neuron–glia Interactions
Glial cells are numerically the dominant cell type in the central and peripheralnervous system. They are intermixed with the nerve cells and are found in intimatecontacts with neuronal cell bodies, dendrites, axons and synaptic contacts. Like neurons,glial cells are a heterogeneous population of cells that differ in developmental origin,molecular composition, structure and activ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Open Pain Journal
سال: 2010
ISSN: 1876-3863
DOI: 10.2174/1876386301003010003